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PDRN Micro Infusion System

PDRN Micro Infusion System

Transform stubborn acne scars and smooth your skin's texture using easy treatments you can do right at home.

ads_click Targets acne scars at the source

rocket_launch Boosts collagen and skin regeneration

health_and_safety Painless, Quick, at-home application

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What is PDRN (Salmon DNA)?

PDRN (Polydeoxyribonucleotide) is a powerful skin-repairing compound derived from salmon DNA.

With proven regenerative and anti-inflammatory properties, it has been widely used in Korean aesthetic clinics for years, primarily for wound healing, post-surgical recovery, and advanced skin rejuvenation treatments.

PDRN is known for its ability to:

  • Stimulate fibroblasts (the cells that produce collagen)
  • Improve tissue regeneration
  • Calm inflammation
  • Accelerate healing from within

We are proud to be one of the first to make this clinically-proven ingredient available as an at-home micro-infusion treatment, so you can get the benefits without the clinic hassle.

How often should I use it?

Just 5 minutes twice a month. Each treatment uses 1 vial and 1 sterile needle head.

Every order comes with a step-by-step video guide and instructions.

Ingredients

Our formula is designed for post-acne skin — focused on repair, regeneration, and hydration. Here are the key ingredients that make the difference:

  • PDRN: Stimulates skin regeneration and collagen synthesis
  • Niacinamide: Improves tone, texture, and barrier function
  • Panthenol: Soothes, hydrates and supports repair
  • Hyaluronic Acid: Deep hydration that plumps and smooths
  • Centella Asiatica Complex: Calms inflammation and boosts healing

Note: Due to the natural properties of the formula, serum color may vary slightly or fade over time. This does not affect its safety or effectiveness.

All ingredients: Water, Glycerin, Butylene Glycol, Trehalose, Panthenol, Niacinamide, 1,2-Hexanediol, Hydroxyacetophenone, Cyclodextrin, Sodium DNA (Salmon DNA), Carbomer, Gentiana Scabra Root Extract, Sodium Hyaluronate, Arginine, Centella Asiatica Extract, Gardenia Florida Flower Extract, Phellodendron Amurense Bark Extract, Caprylyl Glycol, Mannitol, Madecassoside, Centella Asiatica Leaf Extract, Adenium Obesum Leaf Cell Extract, Asiaticoside, Soluble Collagen

Is it painless and easy to use?

Yes! Our 0.5mm gold-tipped stamp is almost painless and designed for minimal sensation and comfort. The process is simple, takes just 5 minutes and comes with a step-by-step video guide and instructions.

Our formula is gentle on even sensitive, post-acne skin.

What makes this different from other treatments?

Most scar treatments are either too aggressive (like lasers) or too superficial (like gels). Derm combines the precision of microneedling with a targeted repair serum, giving you the power of a clinic-grade treatment — at home, without pain or recovery time.

What's included?

Each Micro-Infusion Kit is designed to provide a specific number of treatments. All sterile needle heads are single-use and should be safely discarded after each session to ensure hygiene and optimal results.

Here’s what’s inside:

  • 1-Month Supply → 2 sterile heads + 2 serum vials (2 treatments)
  • 2-Month Supply → 4 sterile heads + 4 serum vials (4 treatments)
  • 3-Month Supply → 6 sterile heads + 6 serum vials (6 treatments)

Each vial and needle head is intended for a single treatment every 2 weeks and should not be reused.

P.S. Every order includes access to a step-by-step video guide to ensure perfect application.

90 Day Money-Back Guarantee

We created this system to help people who’ve tried everything — and we stand behind it completely. If you don’t see visible improvements in your skin within 90 days, we’ll refund your order.

For returns, please email us at tryskynncosmetics.com

View full details
  • Fragrance-Free

  • Alcohol-Free

  • No Artificial Colorants

  • Dermatologically Tested

     
     
    Real Skyyn
    Transformations
    Skyyn is rated "Excellent" based on 1,400+ reviews
    Video Testimonial Soon

    Deep Boxcar Scars & Enlarged Pores

    Brittney H. Verified Customer
    • Deep cheek scars look less visible
    • Pores appear more refined
    • Confidence regained, no more heavy makeup

    "I thought these scars were permanent… but after just a few treatments, I started to see the dents fade. It’s the first time I’ve felt confident without covering everything up. This honestly saved me from spending thousands at a clinic"

    Video Testimonial Soon

    Ice Pick & Pitted Scars

    Nicolay L. Verified Customer
    • Scars are visibly less deep and smoother
    • Skin tone looks more even and uniform
    • No more makeup needed for photo shoots

    "I thought these scars were permanent... but after just a few treatments, I started to see the dents fade."

    Video Testimonial Soon

    Rolling Scars & Large Pores

    Marie P. Verified Customer
    • Scars visibly reduced and pores appear tighter
    • Texture looks smoother and more even
    • Visible transformation after just 5 treatments

    "My scars were deep and obvious… now they’re so much more subtle. I’m finally feeling confident!"

    Video Testimonial Soon

    Post-Acne Scars & Skin Texture

    Gina P. Verified Customer
    • Chin scars visibly faded in just 3 treatments
    • Texture looks smoother, less “pitted”
    • No longer feels the need for heavy makeup

    "I thought these acne scars would be with me forever. But now, they’re almost gone. My skin looks and feels smooth, I’m honestly shocked at how fast this worked."


    Why Our Micro Infusion Technology

    Why Our Micro Infusion Technology Works When Others Don't

    Using ultra-fine 24K gold sterile microneedles, creates tiny channels for deep serum penetration—targeting acne scars at their source
    0%
    experienced smoother texture and more balanced skin tone
    0%
    observed clear reduction in post-acne scar visibility
    0%
    reported healthier, firmer, deeply hydrated skin

    The Revolutionary Formula That Separates Us from the Rest

    KEY INGREDIENTS
    + PDRN (Salmon DNA)
    A skin-regenerating molecule that stimulates collagen production and accelerates cellular repair — helping visibly improve scar depth, texture, and resilience over time.
    + Niacinamide
    A multitasking active that evens out tone, fades post-acne marks, and strengthens the skin barrier — ideal for sensitive or inflamed skin.
    + Panthenol (Pro-Vitamin B5)
    Profoundly comforting and reparative, it reduces redness and encourages deep skin recovery after acne flare-ups or intensive procedures.
    + Hyaluronic acid
    Provides intense hydration while supporting elasticity and plumpness — essential for softening atrophic acne scars and improving skin texture.

    Fade Acne Scar in 4 Simple Steps

    Just 5 minutes every 2 weeks.
    1
    Cleanse & Prepare
    Wash your face thoroughly and gently pat until dry. Ensure your skin is fresh and primed for maximum absorption
    2
    Connect & Load
    Screw the serum vial directly into the microneedle head. Turn the device upside down for approximately 2 minutes so the serum fully saturates the needles.
    3
    Stamp & Treat
    Lightly press the device against your skin, beginning at the face's center and working outward with half overlapping strokes. Go over targeted areas 2–3 times
    4
    Let It Work
    Gently tap leftover serum into your skin and leave on through the night. Keep away from cosmetics and direct sunlight for 24 hours.

    See The Difference. Feel The Results.
    SKYYN
    Features
    AggressiveClinical Treats
    Basic At-Home Microneedling
    Topical Scar Creams/Serums
    Targets Deep Texture Scars
    Clinic-Level Results from Home
    No Pain or Extreme Discomfort
    No Risk of Worsening Scars
    Safe for Sensitive & Compromised Skin

    Professional Results Without the Professional Price

    Scar Repair Shouldn’t Cost Thousands
    You could spend each year:
    • $3,000+ on laser treatments with long recovery times
    • $1,800+ on microneedling or filler combos
    • $1,100+ trying every scar serum on the market

    Or, get 6 full treatments and start seeing change from home — for a fraction of the cost of a single clinic session.

    Questions?

    When will I start seeing results?

    Many users notice smoother, more hydrated skin after just one treatment — often describing a fresh glow and softer texture within 24–48 hours. That’s because the micro-infusion process immediately boosts hydration and wakes up your skin’s repair response.

    However, acne scar repair is a long-term process.

    For visible, lasting improvement, we recommend completing at least 6 treatments over 3 months.

    How does this work on acne scars?

    It combines precision microneedling with a clinically formulated scar-repair serum.

    The ultra-fine painless 24K gold needles create micro-channels in your skin, allowing the serum to reach the deeper layers where scars actually form.

    The result? Stimulated collagen production, improved skin texture, and a visible reduction in scar depth over time.

    Does it help with deeper scars?

    Yes, it does! The PDRN Micro Infusion System is designed to help improve deep acne scars by stimulating collagen and repairing the skin from within.

    It takes consistency, usually a full 3-month cycle (6 treatments), but many people see visible improvement in scar depth and texture over time.

    How many treatments are included, and how often should I use it?

    Micro Infusion System includes single-use sterile microneedle heads and serum vials.

    1-Month Supply → 2 treatments (2 needle heads and 2 serum vials)
    2-Month Supply → 4 treatments (4 needle heads and 4 serum vials)
    3-Month Supply → 6 treatments (6 needle heads and 4 serum vials)

    We recommend one session every 2 weeks to give your skin time to regenerate properly. This rhythm supports long-term collagen activation and minimizes irritation.

    After each session, it is recommended to dispose of the used needle head and any apply any remaining serum on your skin.

    Each order comes with an easy to follow step-by-step video guideline.

    Is it painless?

    The device uses ultra-fine, sterile 24K gold microneedles designed to gently penetrate only the uppermost layer of skin.

    While they are long enough to trigger collagen and increase serum absorption, they are also thinner than a human hair, which makes the treatment very tolerable — even for beginners.

    You might feel a light tingling or pricking during application, especially in more sensitive areas. But there’s no dragging, tearing, or numbing required.

    Most people describe it as a gentle tapping sensation — and get used to it within seconds.

    What is the length of the needles?

    Skyyn’s micro-infusion system uses microneedles that are 0.5mm in length — ideal for what's called “epidermal needling.”

    This depth allows the serum to reach the upper dermis, where acne scars form, without causing pain or requiring medical supervision.

    It’s long enough to:
    - Stimulate collagen production
    - Boost cellular renewal
    - Enhance absorption of active ingredients up to 30x more effectively than topical application

    At the same time, it's short enough to avoid bleeding or downtime, making it perfectly safe for at-home use — even for beginners.

    What is the percentage of PDRN (Salmon DNA) inside the formula?

    Our formula contains 0.2% PDRN — an ideal concentration for at-home use, especially when paired with micro-infusion, which enhances absorption compared to regular topical application.

    Because our system infuses the ingredients directly into the upper layers of the skin, the PDRN is absorbed more efficiently than it would be in a standard serum.

    This means:
    - 0.2% delivered through micro-infusion can be more effective in practice
    - Topical serums with higher percentages often remain mostly on the surface
    - You get meaningful results while keeping the formula gentle and safe

    This balance ensures a treatment that is effective, well-tolerated, and suitable for consistent use at home.

    At the same time, it's short enough to avoid bleeding or downtime, making it perfectly safe for at-home use — even for beginners.

    Is this FDA approved?

    The micro-infusion device itself is not FDA-approved yet.

    Our manufacturer is currently in the process of obtaining FDA 510(k) clearance for the microneedle stamp, but this review takes time and is still ongoing.

    The serum component is FDA-listed under MoCRA, which is the FDA’s regulation framework for cosmetic products.

    Both the device and serum are produced in an FDA-registered, GMP-certified, and ISO 22716–compliant facility, ensuring controlled production, sterile conditions, and consistent quality across every batch.

    How is the product manufactured?

    Our PDRN micro-infusion system is produced using 17 fully automated production lines in a pharmaceutical-grade environment.

    Each batch follows strict international standards (GMP, GMPC, ISO 22716), with raw materials sourced from world-leading suppliers and tested for purity, microbiology, and safety.

    The facility is FDA-registered, and core processes occur in a Class 100 sterile cleanroom using ultrapure medical-grade water.

    Is it suitable for sensitive or darker skin tones?

    Yes. Our formula and delivery system are both designed to be non-comedogenic, non-irritating, and safe for all skin types and tones.

    We don’t use harsh acids, retinoids or bleaching agents. If your skin is extremely reactive, we recommend a patch test first, or consulting a dermatologist.

    How long does redness or irritation last after a treatment? If I have a treatment on Friday night, will my skin look normal again by Monday?

    Most people only notice slight redness immediately after treatment, which usually disappears within a few hours or at most a day.

    By Monday, the skin should return to normal, so it is advisable to undergo treatment on Friday evening.

    We also always recommend doing a patch test on your wrist and leaving it on for 24 hours.